Trabeculectomy Surgery in Primary and Secondary Glaucoma: Retrospective Cross-sectional Analysis
DOI:
https://doi.org/10.55018/janh.v7i2.333Keywords:
Primary Glaucoma, Secondary Glaucoma, Intraocular Pressure, Trabeculectomy, Surgical OutcomesAbstract
Background: Glaucoma remains a leading cause of permanent blindness worldwide, with elevated intraocular pressure (IOP) as the most modifiable risk factor. When medical therapy fails, trabeculectomy is often the preferred surgical option, though its effectiveness may differ based on the type of glaucoma. Primary glaucoma is typically idiopathic, while secondary glaucoma results from identifiable causes such as trauma, inflammation, or diabetes. Understanding these distinctions is essential for optimizing surgical outcomes and tailoring patient-specific treatment strategies. This study aims to determine whether there is a difference between the reduction in intraocular pressure in primary and secondary glaucoma after undergoing trabeculectomy surgery.
Methods: This descriptive cross-sectional study used purposive sampling to select medical records of patients who underwent trabeculectomy at the Christian University of Indonesia Teaching Hospital from July 2021 to June 2022. A total of 30 patients were included. Inclusion criteria were patients diagnosed with either primary or secondary glaucoma who underwent trabeculectomy and had complete pre- and postoperative IOP data. Exclusion criteria included patients with previous glaucoma surgery, incomplete medical records, or less than one month of follow-up. The primary outcome was the percentage reduction in IOP one month postoperatively..
Results: The results showed that the percentage reduction in IOP within 1 month in primary glaucoma was 43.54%, whereas in secondary glaucoma, it was 41.87%. P value > 0.05 in all postoperative IOPs between primary glaucoma and secondary glaucoma.
Conclusion: Trabeculectomy is still the first choice to reduce IOP, which has failed pharmacological treatments. However, there was no significant difference between decreased intraocular pressure in patients with primary and secondary glaucoma.
Downloads
References
Allison, K., Patel, D., & Alabi, O. (2020). Epidemiology of glaucoma: the past, present, and predictions for the future. Cureus, 12(11). https://www.cureus.com/articles/42672-epidemiology-of-glaucoma-the-past-present-and-predictions-for-the-future.pdf
Aung, T., Tow, S. L. C., Yap, E.-Y., Chan, S.-P., & Seah, S. K. (2000). Trabeculectomy for acute primary angle closure. Ophthalmology, 107(7), 1298–1302. https://www.sciencedirect.com/science/article/pii/S0161642000001378
Christine, R. N., Sinurat, V. L., Simanjuntak, G. W. S., & Tan, J. F. (2021). Hubungan Antara Usia, Tekanan Intraokular, dan Komorbid Terhadap Keberhasilan Trabekulektomi pada Pasien Glaukoma Primer. Jurnal Oftalmologi, 3(2), 33–37. http://repository.uki.ac.id/5200/
Conlon, R., Saheb, H., & Ahmed, I. I. K. (2017). Glaucoma treatment trends: a review. Canadian Journal of Ophthalmology, 52(1), 114–124. https://www.sciencedirect.com/science/article/pii/S0008418216300758
Dizayang, F., Bambang, H., & Purwoko, M. (2020). Karakteristik Penderita Glaukoma di Rumah Sakit Muhammadiyah Palembang Periode Januari 2017-April 2018. Journal of Health Sciences, 13(01), 66–73. http://journal2.unusa.ac.id/index.php/JHS/article/view/1146
Fea, A. M., Bertaina, L., Consolandi, G., Damato, D., Lorenzi, U., & Grignolo, F. M. (2012). Angle Closure Glaucoma: Pathogenesis and Evaluation. A Review. J Clinic Experiment Ophthalmol S, 4, 1–7. https://www.academia.edu/download/85828399/angle-closure-glaucoma-pathogenesis-and-evaluation-a-review-2155-9570.S4-005.pdf
Kanaya, R., Kijima, R., Shinmei, Y., Shinkai, A., Ohguchi, T., Namba, K., Chin, S., & Ishida, S. (2021). Surgical Outcomes of Trabeculectomy in Uveitic Glaucoma: A Long-Term, Single-Center, Retrospective Case-Control Study. Journal of Ophthalmology, 2021, 1–8. https://doi.org/10.1155/2021/5550776
Kansal, V., Armstrong, J. J., & Hutnik, C. M. (2020). Trends in Glaucoma Filtration Procedures: A Retrospective Administrative Health Records Analysis Over a 13-Year Period in Canada. Clinical Ophthalmology, Volume 14, 501–508. https://doi.org/10.2147/OPTH.S232873
Kono, Y., Kasahara, M., Hirasawa, K., Tsujisawa, T., Kanayama, S., Matsumura, K., Morita, T., & Shoji, N. (2020). Long-term clinical results of trabectome surgery in patients with open-angle glaucoma. Graefe’s Archive for Clinical and Experimental Ophthalmology, 258, 2467–2476. https://idp.springer.com/authorize/casa?redirect_uri=https://link.springer.com/article/10.1007/s00417-020-04897-0&casa_token=OlG48LLwv4cAAAAA:WPkNMi8uxDAuq9G4YdVYtKeSXsfNgmZpvgzlsijMg2vpA9xTm73ifsjvS3DY8JabXchuj63Riqz3wF4AgQ
Kyei, S., Owusu-Afriyie, B., Tagoh, S., Kwarteng, M. A., Nsiah, P., & Guramatunhu, S. (2021). Clinical and sociodemographic characteristics of glaucoma patients at a tertiary referral facility in Zimbabwe. Malawi Medical Journal, 33(1), 15–20. https://www.ajol.info/index.php/mmj/article/view/206429/194678
Maeda, M., Watanabe, M., & Ichikawa, K. (2013). Evaluation of trabectome in open-angle glaucoma. Journal of Glaucoma, 22(3), 205–208. https://journals.lww.com/glaucomajournal/fulltext/2013/03000/Evaluation_of_Trabectome_in_Open_Angle_Glaucoma.6.aspx
Maulida, F., Rahmi, F. L., & Cahyono, M. (2021). Success rate of trabeculectomy in secondary glaucoma after vitrectomy in Kariadi Hospital, Semarang, Central Java. Ophthalmologica Indonesiana, 47(2), 73–78. https://ophthalmologica-indonesiana.com/index.php/journal/article/view/100312
Nugraha, S., Kusumadjaja, A., & Andayani, A. (2019). KEBUTAAN OLEH KARENA PRIMARY ANGLE CLOSURE GLAUCOMA PADA RUMAH SAKIT UMUM PUSAT SANGLAH DENPASAR. Jurnal Kedokteran Universitas Palangka Raya, 7(1), 740–746. https://e-journal.upr.ac.id/index.php/JK/article/view/576
Pantalon, A., Feraru, C., Tarcoveanu, F., & Chiselita, D. (2021). Success of Primary Trabeculectomy in Advanced Open Angle Glaucoma. Clinical Ophthalmology, Volume 15, 2219–2229. https://doi.org/10.2147/OPTH.S308228
Perpustakaan Kemenkes RS Mata Cicendo Portal Perpustakaan RSM Cicendo Road Map of Visual Impairment Control Program in Indonesia 2017 – 2030. (2019). https://elib.cicendoeyehospital.org/2019/04/08/road-map-of-visual-impairment-control-program-in-indonesia-2017-2030/
Sambhara, D., & Aref, A. A. (2014). Glaucoma management: relative value and place in therapy of available drug treatments. Therapeutic Advances in Chronic Disease, 5(1), 30–43. https://doi.org/10.1177/2040622313511286
Senthil, S., Chinta, S., Rao, H. L., Choudhari, N. S., Pathak-Ray, V., Mandal, A. K., & Garudadri, C. S. (2016). Comparison of cataract surgery alone versus cataract surgery combined with trabeculectomy in the management of phacomorphic glaucoma. Journal of Glaucoma, 25(3), e209–e213. https://journals.lww.com/glaucomajournal/fulltext/2016/03000/comparison_of_cataract_surgery_alone_versus.31.aspx
Shinohara, Y., Akiyama, H., Magori, M., & Kishi, S. (2017). Short-term outcomes after EX-PRESS implantation versus trabeculectomy alone in patients with neovascular glaucoma. Clinical Ophthalmology, Volume 11, 2207–2213. https://doi.org/10.2147/OPTH.S151200
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Reinne Natali Christine, Nicolas Dwiki Tanong, Claudia Claudia, Frisca Angreni
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
