Effectiveness of Honey Soy Milk on Hemoglobin Improvement among Adolescent Girls with Menstrual Anemia: A Quasi-Experimental Study
DOI:
https://doi.org/10.55018/janh.v8i1.430Keywords:
Adolescent, Anemia, Iron-Deficiency, Hemoglobins, Soy MilkAbstract
Background: Anemia is a common health problem among adolescent girls, primarily due to iron deficiency and blood loss during menstruation. Honey contains bioactive compounds beneficial to health, including the improvement of metabolism and hematological status. This study aims to determine the effect of honey soy milk on hemoglobin (Hb) levels among adolescent girls with menstrual anemia.
Methods: This quantitative study employed a quasi-experimental design with one group pretest–posttest, conducted at an educational institution in Indonesia. A total of 25 adolescent girls with menstrual anemia were selected using purposive sampling based on inclusion and exclusion criteria. The intervention consisted of administering 200 mL of honey soy milk twice daily for 5 consecutive days during menstruation. Hemoglobin levels were measured in g/dL using an EasyTouch GCHb digital analyzer before and after the intervention. Data analysis followed the Transparent Reporting of Evaluations with Nonrandomized Designs (TREND) guidelines.
Results: The mean hemoglobin level before the intervention was 11.15 ± 1.72 g/dL, and after the intervention, it increased to 12.92 ± 1.87 g/dL. Statistical testing showed a significant difference (p < 0.001), indicating that honey soy milk effectively improved Hb levels among participants.
Conclusion: Honey soy milk is effective in increasing hemoglobin levels in adolescent girls with menstrual anemia. These findings support the use of functional foods as an adjunctive strategy in anemia prevention and management programs for adolescents
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Abdi, M., Beigzadeh, A., Hayat, A. A., Keshavarzi, M. H., & Rezaei, H. (2025). Effectiveness of a short course in communication skills for medical doctors: Evaluation based on a one-group pretest–posttest design. Research and Development in Medical Education, 14(1), 33267. https://doi.org/10.5812/rdme.33267
Abdullah, I., Ilmiah, W. S., Prihatono, A., & Kurniawan, L. C. (2024). Group 1st of non-pharmacological therapy that is most effective to increase hemoglobin in pregnancy. Jurnal Promkes: The Indonesian Journal of Health Promotion and Health Education, 12(1), 219–226. https://doi.org/10.20473/jpk.v12i1.2024.219-226
Althubaiti, A. (2023). Sample size determination: A practical guide for health researchers. Journal of General and Family Medicine, 24(2), 72–78. https://doi.org/10.1002/jgf2.603
An, R., Huang, Y., Man, Y., Valentine, R. W., Kucukal, E., Goreke, U., Sekyonda, Z., Piccone, C., Owusu-Ansah, A., & Ahuja, S. (2021). Emerging point-of-care technologies for anemia detection. Lab on a Chip, 21(10), 1843–1865. https://doi.org/10.1039/D1LC00030A
Asrida, A., Astuti, A., Leli, L., & Saad, R. (2022). Effect of honey on hemoglobin levels and 8-hydroxy-2-deoxyguanosine (8-OHdG) in pregnant women with anemia. Journal of Asian Multicultural Research for Medical and Health Science Study, 3(3), 25–31. https://doi.org/10.47616/jamrmhss.v3i3.287
Berg, A., & McCarthy, H. D. (2022). A soy-yoghurt-honey product as a therapeutic functional food: Mode of action and narrative review. Heliyon, 8(11), e11276. https://doi.org/10.1016/j.heliyon.2022.e11276
Bhui, K., Newbury, J. B., Latham, R. M., Ucci, M., Nasir, Z. A., Turner, B., O’Leary, C., Fisher, H. L., Marczylo, E., & Douglas, P. (2023). Air quality and mental health: Evidence, challenges and future directions. BJPsych Open, 9(4), e120. https://doi.org/10.1192/bjo.2023.120
Christa, B., Khairunnisa, H. I., & Saryono, S. (2023). The effectiveness of honey consumption on increasing hemoglobin levels in young women: A systematic review. International Journal of Biomedical Nursing Review, 2(3), 25–34. https://doi.org/10.37275/ijbnr.v2i3.384
De, B., & Goswami, T. K. (2022). Micronutrient fortification in foods and soy milk, a plant-based milk substitute as a candidate vehicle. Current Nutrition & Food Science, 18(8), 739–745. https://doi.org/10.2174/1573401317666210726110942
Eichler, K., Hess, S., Twerenbold, C., Sabatier, M., Meier, F., & Wieser, S. (2019). Health effects of micronutrient-fortified dairy products and cereal food for children and adolescents: A systematic review. PLOS ONE, 14(1), e0210899. https://doi.org/10.1371/journal.pone.0210899
Fekete, M., Lehoczki, A., Kryczyk-Poprawa, A., Zábó, V., Varga, J. T., Bálint, M., Fazekas-Pongor, V., Csípő, T., Rząsa-Duran, E., & Varga, P. (2025). Functional foods in modern nutrition science: Mechanisms, evidence, and public health implications. Nutrients, 17(13), 2153. https://doi.org/10.3390/nu17132153
Fitripancari, A. D., Arini, F. A., Imrar, I. F., & Maryusman, T. (2023). The relationship between iron and vitamin C intake, risk beverage consumption frequency, and dietary behavior with anemia among adolescent girls. Amerta Nutrition, 7(2), 91–98. https://doi.org/10.20473/amnt.v7i2.2023.91-98
Hardiansyah, A., Khasanah, A. N., & Hayati, N. (2024). Correlation between iron consumption, hemoglobin level, and nutritional status on the physical fitness of young women. Amerta Nutrition, 8(3), 230–238. https://doi.org/10.20473/amnt.v8i3.2024.230-238
Hu, M., Zhou, J., Qiu, L., Song, R., Qin, X., Tan, Z., Wang, W., Liu, R., Li, Y., & Mao, Y. (2024). Effects of soy protein on alleviating iron deficiency anemia in suckling rats with different iron supplements. Food Bioscience, 61, 104555. https://doi.org/10.1016/j.fbio.2024.104555
Ilia, G., Simulescu, V., Merghes, P., & Varan, N. (2021). The health benefits of honey as an energy source with antioxidant, antibacterial, and antiseptic effects. Science & Sports, 36(4), 272.e1–272.e7. https://doi.org/10.1016/j.scispo.2020.09.003
Kim, I.-S. (2021). Current perspectives on the beneficial effects of soybean isoflavones and their metabolites for humans. Antioxidants, 10(7), 1064. https://doi.org/10.3390/antiox10071064
Kumar, S. B., Arnipalli, S. R., Mehta, P., Carrau, S., & Ziouzenkova, O. (2022). Iron deficiency anemia: Efficacy and limitations of nutritional and comprehensive mitigation strategies. Nutrients, 14(14), 2976. https://doi.org/10.3390/nu14142976
Munro, M. G. (2023). Heavy menstrual bleeding, iron deficiency, and iron deficiency anemia: Framing the issue. International Journal of Gynecology & Obstetrics, 162(S1), 7–13. https://doi.org/10.1002/ijgo.14694
Olías, R., Delgado-Andrade, C., Padial, M., Marín-Manzano, M. C., & Clemente, A. (2023). An updated review of soy-derived beverages: Nutrition, processing, and bioactivity. Foods, 12(14), 2665. https://doi.org/10.3390/foods12142665
Polushkina-Merchanskaya, O., Armstrong, M. D. S., Gomez-Llorente, C., Ferrer, P., Fernandez-Gonzalez, S., Perez-Cruz, M., Gomez-Roig, M. D., & Camacho, J. (2025). Considerations for missing data, outliers, and transformations in permutation testing for ANOVA with multivariate responses. Chemometrics and Intelligent Laboratory Systems, 258, 105320. https://doi.org/10.1016/j.chemolab.2025.105320
Riskesdas. (2023). Laporan nasional Riskesdas 2023: Hasil utama riset kesehatan dasar. Badan Penelitian dan Pengembangan Kesehatan, Kementerian Kesehatan Republik Indonesia. https://www.litbang.kemkes.go.id
World Health Organization. (2011). Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity. https://www.who.int/publications/i/item/WHO-NMH-NHD-MNM-11.1
World Health Organization. (2021). Comprehensive implementation plan on maternal, infant and young child nutrition: 2025 targets progress and way forward. https://www.who.int/publications/i/item/978924003258
World Health Organization. (2023). The global prevalence of anaemia in women of reproductive age (2000–2021): WHO estimates. https://www.who.int/publications/i/item/9789240071115
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