The Effect of Tempeh Dietary Intake on Blood Glucose Levels in Prediabetics
DOI:
https://doi.org/10.55018/janh.v8i1.469Keywords:
empeh, Prediabetes, Blood Glucose, Fermented Soy, Dietary InterventionAbstract
Background: Rediabetes is a high-risk metabolic condition that precedes type 2 diabetes mellitus and is associated with increased morbidity. Dietary intervention plays a critical role in glycemic control. Tempeh, a traditional fermented soybean product, contains bioactive compounds such as isoflavones and high-quality protein that may improve glucose metabolism. However, evidence on its effectiveness in prediabetic populations remains limited. This study aimed to evaluate the effect of daily tempeh consumption on blood glucose levels among individuals with prediabetes.
Methods: A comparative pre-experimental study with a pretest–posttest control group design was conducted at Mohammad Hoesin Hospital, Palembang. A total of 60 participants with prediabetes were randomly assigned to intervention (n=30) and control (n=30) groups. The intervention group received 250 g/day of tempeh for 14 days, while the control group followed a regular diet. Blood glucose levels were measured before and after the intervention. Data were analyzed using paired and independent t-tests with a significance level of p<0.05.
Results: Baseline characteristics between groups were comparable (p>0.05). The intervention group showed a significant reduction in mean blood glucose levels from 139.83±16.52 mg/dL to 104.30±13.11 mg/dL (p<0.001), while the control group also showed a smaller decrease from 137.83±14.87 mg/dL to 121.93±13.09 mg/dL (p<0.001). The mean reduction was significantly greater in the intervention group (35.53 mg/dL) compared to the control group (15.90 mg/dL), with a statistically significant between-group difference (p<0.001).
Conclusion: Daily consumption of 250 g tempeh for 14 days significantly reduces blood glucose levels in individuals with prediabetes. Tempeh may serve as an effective dietary strategy for glycemic control and prevention of diabetes progression.
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References
A. C. Guyton. (2019). Buku Ajar Fisiologi Manusia dan mekanisme Penyakit Edisi 13. Elsevier.
Astawan, M. (2019). Pengaruh konsumsi tempe dari kedelai germinasi dan non-germinasi terhadap profil darah tikus diabetes. Jurnal Pangan, 28(2), 135–144. https://doi.org/https://doi.org/10.33964/jp.v28i2.439
Basir, I. S., & Arsad, S. F. M. (2025). Pendampingan Modifikasi Gaya Hidup (Pola Makan & Aktivitas Fisik) untuk Menurunkan Kadar Gula Darah pada Pasien Pradiabetes. Sambulu Gana: Jurnal Pengabdian Masyarakat, 4(1), 1–6. https://doi.org/https://doi.org/10.56338/sambulu_gana.v4i1.6272
Dafriani, P., & Dewi, R. I. S. (2019). Tingkat Pengetahuan pada Pasien Diabetes Melitus (DM) Tipe 2. Jurnal Abdimas Saintika, 1(1), 45–50. https://doi.org/http://dx.doi.org/10.30633/jas.v1i1.467
Dewantari, N. M., & Sukraniti, D. P. (2020). Efek konseling germas terhadap implementasi germas dan indeks massa tubuh wanita dewasa di pusat kebugaran. AcTion: Aceh Nutrition Journal. AcCion: Aceh Nutrition Journal, 5(1), 62–70. https://doi.org/http://dx.doi.org/10.30867/action.v5i1.209
Indrawati, I., & Maimaznah, M. (2020). Pengaruh konsumsi tempe terhadap kadar gula darah pada penderita diabetes melitus di kelompok senam ibu-ibu di Kelurahan Talang Banjar Jambi. Jurnal Akademika Baiturrahim Jambi, 9(1), 110–114. https://doi.org/https://doi.org/10.36565/jab.v9i1.195
K Azizah. (2020). 12 Manfaat tempe bagi kesehatan, makanan murah dengan khasiat mahal. Merdeka. MERDEKA. https://www.merdeka.com/trending/12-manfaat-tempe-bagi-kesehatan-makanan-murah-dengan-khasiat-mahal-kln.html
Kriswiastiny, R., Hadiarto, R., & Prasetia, T. (2022). Hubungan Lama Menderita Diabetes Melitus dan Kadar Gula Darah dengan Kadar Kreatinin Pasien Diabetes Melitus Tipe 2 pada Perempuan dan Laki-Laki. Medical Profession Journal of Lampung, 12(3), 413–420. https://doi.org/https://doi.org/10.53089/medula.v12i3.373
Kurniawan, D. A., Sholeh, M., & Zulkhi, M. D. (2022). The influence of application of local-wisdom-based modules toward peace-loving characters of elementary school students. Indonesian Journal on Learning and Advanced Education (IJOLAE), 157–170. https://doi.org/https://doi.org/10.23917/ijolae.v4i2.17068
Laila, S., & Veronika, E. (2024). Faktor yang Berhubungan dengan Diabetes Melitus Tipe 2. Surya Medika: Jurnal Ilmiah Ilmu Keperawatan Dan Ilmu Kesehatan Masyarakat, 19(1), 18–26. https://doi.org/https://doi.org/10.32504/sm.v19i01.992
Marie Chantal Canivenc. (2023). Beneficial role of dietary phytoestrogens in obesity and diabetes. The American Journal of Clinical Nutrition, 76(6), 1191–1201. https://doi.org/https://doi.org/10.1093/ajcn/76.6.1191
Milita, F., Handayani, S., & Setiaji, B. (2021). Kejadian diabetes mellitus tipe II pada lanjut usia di Indonesia (analisis riskesdas 2018). Jurnal Kedokteran Dan Kesehatan, 17(1), 9–20. https://doi.org/https://doi.org/10.24853/jkk.17.1.9-20
Nurohmi, S., Marfu’ah, N., Naufalina, M. D., Farhana, S. A. H., & Riza, M. E. (2021). Rasio lingkar pinggang-pinggul dan kaitannya dengan kadar kolesterol total pada wanita dewasa. Nutri-Sains: Jurnal Gizi, Pangan Dan Aplikasinya, 4(1), 25–38. https://doi.org/https://doi.org/10.21580/ns.2020.4.1.4706
Perkeni. (2021). Pedoman Pengelolaan dan Pencegahan DM Tipe 2 Dewasa Indonesia.
PERSAGI. (2019). Penutun Diet dan Terapi Gizi Edisi 4. EGC.
Putri, H. R. (2024). Pembuatan Tempe Edamame sebagai Media untuk Mengimplementasikan Biotechnopreneurship pada Mahasiswa Pendidikan Biologi UNIPAR Jember. BIO-CONS: Jurnal Biologi Dan Konservasi, 6(1), 153–162. https://doi.org/https://doi.org/10.31537/biocons.v6i1.1755
Rahadiyanti Ayu dan Tatik Mulyati. (2017). Efek Tempe Kedelai Terhadap Penurunan Kadar Glukosa Darah Pada Prediabetes. Darussalam Nutrition Journal, 1(2), 19–30. https://doi.org/https://doi.org/10.21111/dnj.v1i2.1346
Redi Aryanta, I. wayan. (2020). Manfaat Tempe Untuk Kesehatan. Widya Kesehatan, 2(1), 44–50. https://doi.org/10.32795/widyakesehatan.v2i1.609
Santi, J. S., dan Septiani, W. (2021). Hubungan penerapan pola diet dan aktifitas fisik dengan status kadar gula darah pada penderita dm tipe 2 di RSUD Petala Bumi Pekanbaru tahun 2020. Jurnal Kesehatan Masyarakat, 9(5), 711–718. https://doi.org/https://doi.org/10.14710/jkm.v9i5.30816
Sari, T., Gracienne, G., Hariesti, R. A., Destra, E., Gunaidi, F. C., & Firmansyah, Y. (2024). Edukasi dan Skrining Pentingnya Pemantauan Obesitas Terhadap Terjadinya Resistensi Insulin Pada Lanjut Usia. Jurnal Pengabdian Bidang Kesehatan, 2(2), 64–67. https://doi.org/https://doi.org/10.57214/jpbidkes.v2i2.71
Sasmita, A. M. D. (2021). Faktor-faktor yang mempengaruhi tingkat kepatuhan berobat pasien diabetes melitus. Jurnal Medika Hutama, 2(4), 1105–1111. http://www.jurnalmedikahutama.com/index.php/JMH/article/view/230
Sutopo, D. (2021). Functional food. Elex Media Komputindo.
Syafii, F., & Yani, A. (2024). Protein content, total isoflavone, and antioxidant capacity of modified tempeh flour based on soybean germination time. Journal of Noncommunicable Diseases Prevention and Control, 2(2), 55–62. https://doi.org/https://doi.org/10.61843/jondpac.v2i2.825
Yuliastuti, L. P. S., Lestari, A., & Kusuma, E. G. (2024). Hubungan Pendidikan Dan Pekerjaan Ibu Dengan Status Gizi Anak Prasekolah Di Tk Sari Asih Sumbawa Besar. Journal of Innovation Research and Knowledge, 4(2), 999–1006. https://doi.org/https://doi.org/10.53625/jirk.v4i2.8088
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